I2/HIO3 IN PEG-H2O: AN ELOQUENT SYSTEM FOR DIRECT IODINATION OF ACTIVATED ARENES

Abstract

Polyethylene glycol (PEG) is found to be an inexpensive, environmentally friendly reaction medium for the iodination of activated aromatic compounds by using I2/ HIO3 to afford the corresponding in excellent yield of the product. The remarkable features of this protocol are high conversion, shorter reaction time, easy work up, benign reaction condition, high selectivity; simple practical procedure, cleaner reaction profile and Polyethylene glycol (PEG) can be recovered and reused.