Journal of Advanced Scientific Research

Exploration of Pristine ZnO and Cobalt Doped ZnO for the Solar Photocatalytic Degradation of Methylene Blue Dye

2024-11-15T09:13:11+00:00

The ZnO and Co-doped ZnO were prepared by eco-friendly and modest route, including thermal disintegration of zinc oxalate (ZnOx) and cobalt-zinc oxalate (CoZnOx) powders, respectively, from a mechano-chemical method. The process of conversion of metal/s oxalate dihydrate to the pristine ZnO and cobalt-doped ZnO was studied with TG-DTG and FTIR spectroscopy. ZnO and Co-doped ZnO crystallites were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), Energy dispersive X-ray (EDX), UV–visible and photoluminescence (PL) spectroscopies. Hexagonal Wurtzite crystallite structures of the aforementioned materials were illustrated from XRD data. The surface morphological investigation was done with SEM. EDX study confirms the elemental purity of materials. Chemical bonding information was obtained from FTIR spectra. Optical properties were studied from UV-visible and photoluminescence spectroscopy. Exploration of pristine ZnO and cobalt-doped ZnO for the solar photocatalytic degradation (PCD) of methylene blue dye has been done in a batch photoreactor. The various related parameters such as photocatalyst amount, initial concentration of dye and pH were also examined for maximum degradation efficiency for mentioned dye.

Antimicrobial Potential of Sphaeranthus indicus Against Staphylococcus aureus: A Computational Approach

2024-11-15T09:13:11+00:00

Sphaeranthus indicus is one of the multipurpose medicinal plants widely used as antimicrobial, wound-healing, anti-arthritics, immunostimulant, immunomodulatory, neuroleptic, etc. activities. Computer-aided drug discovery/design (CADD) methods have been developed to identify the promising compounds with advantage over complexity, cost, time consumption, risk and may lead to their development as drugs. The aim of this study is to evaluate the antimicrobial potential of phytochemicals from Sphaeranthus indicus through Molecular docking and ADMET prediction. In this study, 54 bioactive compounds from Sphaeranthus indicus were tested against four bacterial target protein tyrosyl tRNA synthetase, Dihydrofolate reductase, Gyrase B and sortase A of Staphylococcus aureus to determine the potential antimicrobial activity of Sphaeranthus indicus. This study is investigated with the help of molecular docking study and ADMET prediction method. 14 compounds were found as potential inhibitor of Staphylococcus aureus by inhibiting either one or four target protein. These compounds were found to be safe and have good ADMET properties and showed promising potentials that may lead to their development as drugs target against Staphylococcus aureus.

Physicochemical and Biological Water Quality Assessment of Local Ponds of Tumakuru, Karnataka, India

2024-11-15T09:13:11+00:00

Water is an essential component of life. The developments, urbanization and load of the various pollutant sources lead to the deterioration of the ponds. Therefore, the study was conducted to assess the physicochemical and biological characteristics of water from the regional ponds of Tumakuru, Karnataka, India. The water samples from six ponds were taken for the study. The physicochemical parameters showed that the pH of the ponds was found to be 7.35, 6.90, 7.21, 7.91, 7.16 and 8.10, respectively. EC was found to be 0.60, 0.19, 0.42, 0.22, 1.43 and 1.0, respectively. The high value of pH and EC shows its nutrient-rich and alkaline nature. Cl was found to be 4.0, 3.0, 4.4, 2.6, 2.4 and 6.8, respectively. Calcium hardness was observed as 1.9, 2.58, 2.34, 1.15, 1.11 and 12.19, respectively. The Biological oxygen demand (BOD) of the samples was found to be 0.1, 1.6, 0.8, 3.3, 1.2 and 0.4 mg/lit, respectively. Qualitative analysis through most probable number (MPN) method was employed. MPN index of water samples which tested satisfactory was < 2 per 100 mL and MPN index of water sample no. WS1, WS3 and WS5 respectively whereas unsatisfactory ranged from 38 to > 1600 per 100 mL of water sample no. WS2, WS4 and WS6, respectively showed that the water was not suitable for domestic uses having s high value of bacterial load. In order to stop the spread of intestinal illnesses, drinking water sources should undergo routine assessment of physicochemical and microbiological quality tests.