A Review on Coronary Stents: With Polymers and without Polymers

Abstract

Polymers have many uses in cardiology, such as coating matrices for drug-eluting stents and stent platforms (scaffolds) during coronary vascular intervention. Current research focuses on biodegradable polymers rather than permanent polymers. Their use may help to lessen undesirable events such as in-stent restenosis, late stent-thrombosis, and hypersensitivity reactions since they disintegrate once their purpose is served. This paper discusses factors affecting tissue and blood cell functions that should be taken into account when assessing the biocompatibility of stent polymers to improve physiologically suitable 3 Polymers are frequently used in cardiology, particularly in coronary vascular intervention, as coating matrices for drug-eluting stents and stent platforms (scaffolds). In addition to permanent polymers, biodegradable polymers are the subject of current study. Since they break down once their function is completed, using them may help prevent unfavorable outcomes such as in-stent restenosis, late stent thrombosis, and hypersensitivity reactions. This review discusses aspects of blood cell and tissue operations that should be taken into account to evaluate the biological compatibility of stent polymer compounds to improve physiologically relevant features after examining recent literature on polymers used in applications related to cardiology. The shape, difference, motion, and future of vascular cells can all be significantly influenced by the characteristics of the supporting material that they are grown. Lastly, a summary of techniques for measuring these parameters in a physiological setting will be provided.