Biological Diversity of Thiophene: A Review

Abstract

Thiophene has been established as the potential entity in the largely growing chemical world of heterocyclic compounds possessing promising pharmacological characteristics. A series of thiophene compounds can be synthesized through various synthetic routes, with diverse pharmacological activities. In future the moiety 8 its derivatives draw a special attention of medicinal chemists to produce various scaffolds with potent biological activities 8 also as a lead pharmacophore of any compounds 8 for clinical investigations. This review provides various synthetic strategies of thiophene analogues.