ADVANCES IN THE STUDIES OF BIOLOGICAL ACTIVITIES AND NOVEL GREEN SYNTHETIC ROUTES FOR PYRAZOLE SCAFFOLDS

Abstract

In the class of heterocyclic compounds, pyrazole is one of the important classes which structure consists shows a ring (5-membered ring) which have the presence of carbon and nitrogen (mainly three carbon (C) atoms and also shows two neighboring nitrogen (N) atoms which has great importance. Pyrazole is very versatile which brings this compound for designing several potent bioactive agents. There are several applications of organic compounds which has pyrazole as a nucleus molecule in different areas which includes the pharmacy and agro-chemical industries. Due to its versatility, there is an increase in the synthesis, analysis of different properties, and also study of various applications of pyrazole and its derivatives. Pyrazole derivatives have exhibited a broad spectrum of biological activities which has created a huge interest in designing new pharmacological agents having pyrazole as a nucleus molecule. This review paper of pyrazole includes the discussion of various methods of its synthesis and applications of pyrazole and its analogues.