A COMPARATIVE STUDY OF THYROID PROFILE IN HEPATITIS B AND C RELATED LIVER CIRRHOSIS

Abstract

The most vibrant organ of the human body is the liver, which happens to be the second-largest organ in the frame next to
the skin. The liver is susceptible to a wide variety of metabolic, toxic, microbial, circulatory, and neoplastic insults. The
study aims to compare the thyroid profile with liver cirrhosis viruses of hepatitis B and hepatitis C. The present
prospective study carried out from September 2016 to December 2018 at Department of Medical Gastroenterology,
Narayana Medical College and Hospital, Nellore. Spearman's rank correlation used to test the relationship between
thyroid profile with liver cirrhosis. For evaluating the accuracy of the liver cirrhosis patients for identifying the thyroid
profile, the Receiver Operating Characteristic (ROC) curve used. The present study concluded that the level of
sensitivity is significantly more in TT4 and fT3 for mild CTPS group. TT3, TT4, and fT3 have shown significant negative
correlation except for TSH and fT4 in the MELD group