SYNTHESIS OF SUBSTITUTED PHENYLETHYLAMINE AND ETHYLAMINE DERIVATIVES AS COGNITION ENHANCERS

Abstract

The objective of the present study was to synthesize phenylethylamine and ethylamine derivatives and their effects on
brain were studied by using passive avoidance paradigm and Morris water maze (MWM). Synthesized compounds were
effective to reverse the memory deficits induced by scopolamine and synthesized compounds showed the neuroprotective
effect but locomotor effects were not significantly affected. This shows that the synthesized compounds are effective to
control the motor coordination.