PHYTOCHEMICAL AND ANTIBACTERIAL SCREENING OF EVOLVULUS ALSINOIDES L. EXTRACTS AGAINST CLINICAL PATHOGENS

Abstract

Medicinal plants have been used to cure a number of diseases. Currently 80% of the world population depends on plant
derived medicine as the first line of primary health care for human beings since it has no side effects. This present study
was carried out on phytochemical screening and antibacterial activity of Evolvulus alsinoides L. against some clinical
pathogens. Phytochemical compounds such as tannin, terpenoids, saponins, flavonoids, carbohydrates are presence in all
the plant extracts. The methanol extract were observed utmost number of phytochemical compounds compared than
other extracts of water and ethanol. The phytochemical composition of flavonoids and steroids may be the reason for the
higher antibacterial activity against different bacterial strains. The maximum zone of inhibition was noted in Evolvulus
alsinoides L. methanol extract against Escherichia coli (25±1.2 mm in diameter) and Klebsiella pneumoniae (22±1.2 mm in
diameter) compared to other gram positive bacteria. The crude extract as well as the isolated compounds found to be
active in this study could be useful for the development of new antimicrobial drugs.