SYNTHESIS OF COBALT FERRITE NANOPARTICLES AND THEIR APPLICATIONS IN HYPERTHERMIA THERAPY

Abstract

Co-ferrite nanoparticles have been prepared by wet chemical route using micelles. Two sets of particles with sizes of
⁓100 nm and ⁓200 nm were obtained by varying the concentration of micelles. The morphological and crystallographic
study of the particles was performed by scanning electron microscope (SEM) and x-ray diffractometer respectively. To
check the suitability of the co-ferrite nanoparticles in magnetic hyperthermia therapy, various magnetic measurements
were carried out in presence of AC and DC magnetic fields. To investigate the suitability of the particles in hyperthermia
therapy hysteresis loss of the particles under the application of AC magnetic field with various frequencies has been
carried out. The parabolic nature of power loss with the frequency of the applied AC field has been verified from
experimental data. From various measurements, it appeared that the particles with an average size ~100 nm have better
efficiency in view of hyperthermia therapy. A large value of the specific absorption rate (SAR) was found from the ac
hysteresis of the particles.