IMPACT OF LONG TERM HEMODIALYSIS ON LIPID PROFILE AMONG CHRONIC RENAL FAILURE PATIENTS- A DESCRIPTIVE STUDY

Abstract

Chronic Renal Failure (CRF) patients are at risk of cardiovascular diseases due to the elevation of various forms of lipids. The present study was done to describe the impact of long term hemodialysis on the levels of lipids profile. A total of 70 patients with chronic renal failure under regular hemodialysis that does not share the same period of dialysis time (4.0357±1.76) per month. We obtained serum samples from patients in the morning after an overnight fast and were analyzed for total cholesterol (TC), triglycerides (TG), HDL, and LDL, VLDL was calculated. Triglyceride and VLDL levels observed significantly higher than the normal, with direct correlation with increase in the number of hemodialysis (P=0:000, r = 0.336), while there was no significant elevation observed in total cholesterol (P =0.561, r = 0.005). HDL (P: 0.468) and LDL-C (P : 0.588) when compared with the number of times of hemodialysis. From this study we are conducted that increase level of triglyceride and VLDL level in the circulation with increase duration times of hemodialysis and they was no effect of hemodialysis on total cholesterol and HDL and LDL-C. So fail of hemodialysis as a treatment to treat the dyslipidemia mainly hypertriglyceridemia.