Gas chromatography mass spectroscopy [GC-MS] analysis of bio-active compoundsfrom Albizia gumifera leaf extract: A sacred indigenous medicinal plant among the Akamba people of lower eastern Kenya.

Abstract

Gas chromatography mass spectroscopy is one of the most  reliable analytical technique that has been widely used in the identification of different bioactive molecules. In this study, Albizia gumifera was identified and selected. The leaf was extracted using solvent of different polarity, and the result showed  that Albizia gumifera ethanol and Albizia gumifea water  had the high percentage yield of 21.22% and 11.14% while Albizia gumifera hexane and Albizia gumifera dichloromethane with the least recovery of 1.92% and 5.34% respectively.The extract were further subjected to phytochemical screening and the result showed  the presence of alkaloid, anthroquinone, phenol, saponin, coumarin flavonoid and essensial oil present in all the extract. The extract were further subjected to Gas chromatography mass  spectroscopic analysis and the result  revealed the presence of 44 bioactives molecule with a unique  fragmentation pattern of keto-enol tautomerism  and resonance   stabilization though  the formation of a  trophylium ion.  From the result of the findings, It can  be concluded that Albizia gumifera  is a unique medicinal  plant with  a special medicinal potential, which can further be utilized in  the synthesis of a drug lead  compound  and as a neutraceutical product