Nanotechnology Integration in Proniosomal Drug Delivery System

Abstract

The scientific revolution that nanotechnology has sparked has resulted in the development of novel dosage forms like liposomes, proniosomes, and niosomes. Proniosomes are the formulation of the dry surfactant coated particles that form niosomal dispersion in a hot aqueous medium immediately upon agitation. This article offers a detailed analysis of proniosomes. They simplify transport, delivery, dosage, and storage while also reducing issues in the vesicular system caused by aggregation, fusion, and pharmaceutical leakage. Stability issues plague conventional vesicular structures like liposomes and proniosomes..This novel method showed promise in improving oral bioavailability to direct medication to a specific site by prolonging the drug's half-life in the bloodstream, this prevents harmful side effects. Proniosomes are investigated and discussed as potentially useful drug delivery systems for a range of medicinal and cosmetic uses. The use of nanotechnology in drug delivery is becoming increasingly important in the creation of novel dosage forms. Nanotechnology has focused a lot of attention on vesicular drug delivery systems like liposomes, proniosomes, and niosomes. Proniosomes are the best type of vesicular carrier. These are dry formulations because proniosomes are surfactant-coated, water-soluble carrier particles. In just a few minutes, they are rehydrated and ready for use on agitation in heated aqueous media to form niosomal dispersion right away. Drugs that are lipophilic or hydrophilic can be added to these proniosomes. Proniosomes reduce the physical stability issues associated with niosomes, such as aggregation, fusion, and leakage. These routes include oral, parenteral, dermal and transdermal, ocular, oralss mucosal, vaginal, pulmonary, and intranasal