Nanocarriers in Drug Delivery Systems: An Overview

Abstract

Nanocarriers have emerged as a transformative technology in drug delivery systems (DDS), offering significant advancements over traditional methods. This review delves into the various types of nanocarriers, including liposomes, polymeric nanoparticles, micelles, dendrimers, and solid lipid nanoparticles, highlighting their unique properties and advantages in targeted drug delivery. Liposomes have demonstrated extraordinary effectiveness in clinical applications due to their biocompatibility. Conversely, polymeric nanoparticles offer improved stability and regulated drug release, which makes them appropriate for a variety of therapeutic treatments. Because of their structural adaptability, micelles and dendrimers provide accurate medication targeting. Solid lipid nanoparticles offer a steady and regulated release mechanism. Drug loading in nanocarriers involves encapsulation, covalent bonding and electrostatic interactions. These nanocarriers offer significant benefits over conventional drug delivery systems, including improved solubility, stability, and controlled release of drugs. The review also explores the mechanisms by which nanocarriers enhance drug delivery. These attributes enable nanocarriers to deliver drugs more efficiently to specific tissues or cells, reducing systemic toxicity and enhancing therapeutic efficacy.