Herbs used for Urolithiasis Activity: A Critical Review

Abstract

Renal stone formation is one of the oldest known diseases, and is referred to as nephrolithiasis. When a stone moves out of the pelvis and progresses toward the rest of the urinary system, such as the ureter, bladder, and urethra, it gives rise to a condition called urolithiasis. Various medicinal herbs are used to manage stones and are potentially effective in lowering the risk of renal failure. This review article aims to highlight medicinal plants and their mechanistic approaches to urolithiasis. The current review explains the mechanism of action of promising active phytoconstituents, such as Quercetin, Lupeol, Epigallocatechin, Ellagic acid, and kaempferol.