MICROWAVE ASSISTED SYNTHESIS AND CHARACTERIZATION OF O-ALKYL OR O-ARYL TRITHIOPHOSPHATE DERIVATIVES OF NICKEL

Abstract

Nickel (II) O-alkyl or O-aryl trithiophosphate of type Ni[SSK(S)POR]2 (where R= Me, Et, Pri, Bui, Ph, o-CH3C6H4, m-CH3C6H4, p-CH3C6H4) have been synthesized by solvent free microwave assisted method from the reaction of Nickel (II) chloride hexahydrate with dipotassium salts of O-alkyl or O-aryl trithiophosphate ligand in 1:2 molar ratio, respectively. Newly synthesized compounds are black colored powdery solids and soluble in common organic solvents like DMSO, CHCl3, CCl4, alcohol etc. These compounds have been characterized by elemental analysis, molecular weight determination and spectroscopic (IR, 1H NMR and 31P NMR) studies. With the help of them octahedral geometry has been proposed for these compounds. These derivatives also show good antibacterial activity against gram positive and gram negative bacteria and comparative study of antibacterial effect has also been made with standard drugs like Imipenem and Linezolid.