SYNTHESIS, STRUCTURE, SPECTRAL CHARACTERIZATION AND BIOLOGICAL STUDIES OF (E)-N'-(2-HYDROXYBENZYLIDENE) HYDRAZINE CARBOTHIOHYDRAZIDE

Abstract

A (E)-N'-(2-hydroxybenzylidene)-hydrazinecarbothiohydrazide viz. (2-hydroxy B) HCT has been produced using 2- hydroxy benzaldehyde and thiocarbohydrazide with the help of microwave light without utilization of solvents and catalysts, as an eco-friendly scheme. The reaction happens in very quick time giving high quantity of yield. Elemental, IR, NMR and mass spectra were used to characterize compound. Assessment of antibacterial action for Staphylococcus aureus and Escherichia coli and antifungal potential for Aspergillus niger and Rhizopus sps was completed for compound. Compound is bioactive even at very low quantities in solution.