ANTIMICROBIAL STUDIES ON NOVEL Ni(II) METAL COMPLEXES WITH SALICYLOYL PYRAZOLE OXIMES: SYNTHESIS AND CHARACTERIZATION

Abstract

In this present report, five Ni(II) metal complexes with substituted salicyloyl pyrazole oxime Schiff bases were synthesized. The synthesized Ni(II) metal complexes were characterized by analytical and spectral methods. The elemental analysis data revealed that the Schiff base Ni(II) complexes have 1:2 (M:L) stoichiometry. The molar conductivity data show them to be non electrolytes. The Schiff bases are bidentate and coordinating through the imine nitrogen and phenolic oxygen of salicyloyl pyrazole oximes. Based on analytical and spectral data, four-coordinate geometry was assigned for all complexes. The electronic absorption spectra suggest the square planer geometry for the complexes. The ligand salicyloyl pyrazole oximes and their Ni(II) complexes were screened against Bacillus subtilis, Staphylococcus aureus, Actinomycetes and Pseudomonas aeruginosa. Thus it can be concluded that most of the ligands and metal complexes posses moderate antimicrobial activity.