FORMULATION AND CHARACTERIZATION OF ANTIDERMATOPHYTIC CREAM FROM ETHANOL EXTRACTS OF CRESCENTIA CUJETE L. DRIED LEAVES

Abstract

The use of natural products like plants as an alternative for prevention and cure of various diseases has been increasing over time. The present study aims to study phytochemical aspects of Crescentia cujete L. as the tree is known to have many active bio compounds that have enormous medicinal properties. The study emphasises on formulation of antidermatophytic cream using dried leaf extract of Crescentia cujete L. Antimicrobial and antioxidant property evaluations are carried out to prove the effects and applications of antidermatophytic cream formulated using ethanolic Crescentia cujete L. Leaves extract. The phytochemical analysis revealed the presence of alkaloids, flavanoids, carbohydrate, saponins, anthraquinones, glycosides, triterpenoids, tannins and phenolic compounds. The cream is envisaged to have stability and best capacity to reduce free radicals. The study demonstrates profoundly better antioxidant, antibacterial and antidermatophytic effects of ethanol extract of dried leaves of Crescentia cujete L. and formulated cream. Consistent activity was obtained in both ethanol extracts and formulated cream.