NANOFORMULATIONS OF KARANJ AND NEEM OIL: PHASE EQUILIBRIUM AND LARVICIDAL ACTIVITY

Abstract

The increasing risk of environmental pollution and health problems in the day-to-day life due to the usage of synthetic pesticides make the role of nanoemulsions very significant. The study is aimed at development of eco-friendly nanoemulsion of non-edible oil such as Karanj oil and Neem oil by using the Tween80 and PEG400 as surfactant and cosurfactant respectively. The phase behaviour of ternary mixtures and nanoformulations was studied by visual observation. The nanoemulsion was found to be stable for the period of one month at 30˚C . The nanoemulsions were characterized by various physicochemical properties such as viscosity, surface tension, pH, droplet size, polydispersity index etc. The Larvicidal activity was studied under 24h of exposure against Aedes agypti and Culex quinquefasciatus larvaes. Rheological study shows the pseudoplastic flow behaviour.