QUALILATIVE SCREENING AND EVALUATION OF ANTIOXIDANT ACTIVITY OF ARTOCARPUS HETEROPHYLLUS BARK

Abstract

The aim of the present investigation was to evaluate the phytochemical constituents, free radical scavenging activities and antioxidant properties of the chloroform, ethyl acetate and methanol extract of bark of Artocarpus heterophyllus. The phytochemicals in the chloroform, ethyl acetate and methanol extract of bark of A. heterophyllus were determined qualitatively and quantitatively using standard methods. The antioxidant activities were carried out by DPPH free radical scavenging assay and reducing power assay. The methanol extract of A. heterophyllus showed good radical scavenging activities and reducing power activities which were found to increase with the increasing concentration of the extract. The study indicated that the presence of the major phytochemicals viz. flavonoids and phenols in the methanol extract of A. heterophyllus were 86.75 mg/g and 524.86 mg/g, respectively. The present study revealed that the methanol extract of leaves of A. heterophyllus showed significant antioxidant activities as well as phenolic and flavonoidal content.