ECO-FRIENDLY SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF POTENTIALLY ACTIVE Β-DIKETONE LIGAND AND ITS TRANSITION METAL COMPLEXES

Abstract

Diketones are key intermediates for the synthesis of core heterocycles such as isoxazole, pyrazole, flavones, triazole, pyrimidine and benzodiazepines. The β-diketone ligand and its transition metal complexes have been manufactured by ultrasound irradiation. The β-diketone is prepared by using Baker-Venkatraman rearrangement and characterized by physical, spectral and analytical data. The moieties β-diketone compound acts as bidentate ligand and co-ordinate with the transition metal atom through β-diketone system. The synthesized compounds have also been screened for in vitro antibacterial and antifungal activity.