FORMULATION AND EVALUATION OF FLOATING DRUG DELIVERY SYSTEM FOR HYDRODYANAMICALLY BALANCED SYSTEMS OF CURCUMIN TABLET TO TREAT STOMACH ULCER

Abstract

The present work focuses on formulation and evaluation of floating drug delivery system for hydrodyanamically balanced systems of curcumin tablet to treat stomach ulcer. Floating drug delivery tablets were designed and the present study focused on the manufacture of FDS using various polymers such as HPC and HPMC K15 and H. Its efficacy in reducing ulcers due to pylori was evaluated. Floating drug delivery tablets were characterized for their weight variation, stiffness, stability, drug content determination, dissolution, in-vitro dissolution studies, IR, floating interval time, inflammation studies, and erosion studies. The developed curcumin floating tablet system is a promising floating drug delivery system for oral continuous administration of curcumin.