NANOSPONGES FOR EFFECTIVE TREATMENT OF ULCERATIVE COLITIS

Abstract

In modern years, nanosponges (NS) have gained marvelous impetus in drug delivery through nanotechnology. Nanosponges are capable of providing solutions for several formulation related problems. Through this review, scientists working in the ground of nanotechnology can have an insight into the techniques of preparation, characterization and applications of NS. Owing to their small size and spongy nature they can bind poorly-soluble drugs within their matrix and recover their bioavailability. They can be crafted for targeting drugs to precise sites, prevent drug and protein deprivation and prolong drug release in a controlled manner. This appraisal attempts to convoluted different schemes of synthesis of NS and their characterization. Factors affecting drug loading and release have been enumerated. Due to their compensation, NS have not only been explored for their pharmaceutical applications but also have large attractiveness in allied sciences, especially in water purification.