ENVIRONMENTALLY BENIGN ALUM CATALYZED EFFICIENT SYNTHESIS OF 2,3- DIHYDROQUINAZOLINE-4(1H)-ONES DERIVATIVES IN WATER

Abstract

Described method consist of eco-friendly procedure for the preparation of 2,3-dihydroquinazoline-4(1H)-ones from equimolar 2-aminobenzamide and substituted aromatic aldehydes in presence of 10% aqueous Alum (K Al(SO4)2• 12H2O). Green impact of reaction significantly enhanced due to use of water as solvent and naturally occurring substance as catalyst. Good to excellent yield of products, simple working strategy and easy purification are the advantage of present methodology.