EFFICIENT SYNTHESIS OF PYRANOPYRAZOLE DERIVATIVES USING SILICA GRAFTED COPPER STANNATECATALYST

Abstract

The CuSnO₃:SiO₂ catalyst was synthesized by hydrothermal method. The polycrystalline products were analyzed by using various physical investigative techniques including XRD, SEM, TEM and BET surface area. The present study deals with one-pot, four component reaction of aldehydes, malononitrile hydrazine hydrate and ethyl acetoacetate in the presence of catalytic amount of Silica grafted CuSnO₃ in ethanol at 70°C to prepare series of pyranopyrazoles. This method gives high yield of pyranopyrazoles in short reaction time with economic availability of the catalyst and easy purification.