IRIDIUM (III) COMPLEXES OF 1-ALKYL -2-{(O-THIOALKYL) PHENYLAZO} IMIDAZOLES: SYNTHESIS, CHARACTERIZATION, DNA BINDING STUDY AND DFT CALCULATION

Abstract

The Ir(III) complexes of 1-Alkyl-2-{(o-thioalkyl)phenylazo}imidazole (SRaaiNR′, 1; R = Me, R/ = Et (a); R = Et, R/ = Me (b); R = R/ = Et (c)), [Ir(SRaaiNR/)(PPh3)Cl2](ClO4) (2) have been synthesized and characterized by elemental, mass and other spectral (IR, UV-Vis, and 1H NMR) analysis. Based on several spectral analysis octahedral geometry has been proposed for the Ir(III) complexes. The DNA binding ability of the complexes (binding constant: 2.49 x 104 to 4.51 x 104) has been studied by absorption and fluorescence spectroscopic measurements. Density functional theory (DFT) computation technique on the optimized geometry of the complexes has been performed to interpret the electronic structures and their spectral properties.