RAPID AND GREENER MICROWAVE ASSISTED SYNTHESIS OF A SERIES OF (SUBSTITUTED-3- BENZYL-5-(3-PHENOXYBENZYLIDENE) THIAZOLIDINE-2,4-DIONE) DERIVATIVES

Abstract

A Novel series of thiazolidine-2, 4-dione compounds was synthesized under microwave irradiation and those compounds were evaluated for their biological property i.e. antimicrobial activity, against two Gram positive and two Gram negative bacterial strains additionally two fungal strains. Among the synthesized derivatives 9b, 9h and 9i were found to be the most effective antimicrobial compounds. All the prepared compounds were characterized for structural confirmation by IR, 1HNMR, 13CNMR and Mass spectroscopy.